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I just got an email from the lab saying "We cannot interpret your celiac disease blood test because of the low IgA level. Low total IgA means that you do not have enough for the tests to be valid. IgA antibody is made in the mucosal lining of the intestines, which is a very large part of the immune system. When you have active Celiac, your body will be pumping out IgA like crazy. It's the antibody reaction that they are looking for. I am not sure if they can just do an IgG based test, which is another part of the blood work.
Most people go for the biopsy when their total IgA is too low. Having elevated liver enzymes is very comon with Celiac Disease so that could be an added clue. They usually go down into normal once people are on the gluten-free diet for a bit. I figured my tests wouldn't be valid, since I hadn't been eating gluten for a month at the time of the blood draw. Would my numbers supposedly be higher on a gluten diet, even if I wasn't Celiac? I'm not convinced quite yet that I have Celiac or even a gluten sensitivity I just don't know.
I had gluten accidentally on Thanksgiving, and the only thing that happened was that I got a headache three days later, so I can't really connect the two events. I think my next step, besides getting my liver enzymes retested, is to go back to gluten for a couple weeks and see what happens. If I feel it's affecting me, I'll do the Enterolab stool test.
My daughter has low IgA as well, so her celiac test was inconclusive. She has tested positive with more sensitive blood tests however. Good luck! What causes IgA deficiency? What are the symptoms of IgA deficiency? How is IgA deficiency diagnosed? How is IgA deficiency treated? What are the complications of IgA deficiency?
Potential complications can include: Diarrhea Sinusitis Bronchitis Eye infection Ear infection Pneumonia Autoimmune disorders Skin infection Asthma Allergic reactions to blood or blood product transfusions Can IgA deficiency be prevented? IgA is found in mucous membranes, especially in the respiratory and digetive tracts. It is also found in saliva, tears, and breastmilk. IgA deficiency is a genetic health problem that can be passed down through families.
Complications for IgA deficiency include asthma, diarrhea, ear and eye infections, autoimmune diseases, and pneumonia. You can limit the spread of germs and illnesses by washing your hands often and staying away from large crowds.
Next steps Tips to help you get the most from a visit to your healthcare provider: Know the reason for your visit and what you want to happen. Before your visit, write down questions you want answered.
Bring someone with you to help you ask questions and remember what your provider tells you. Ask if your condition can be treated in other ways.
Know why a test or procedure is recommended and what the results could mean.
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